Obesity and COVID-19: a dangerous dyad

Authors

Keywords:

obesidad, resistencia a la insulina, enfermedad por coronavirus 2019, COVID-19, SARS-CoV-2, inmunidad, inflamación.

Abstract

A literature review was conducted on the links of obesity with adverse outcomes of SARS-CoV-2 infection. With the descriptors COVID-19, SARS-CoV-2, and obesity taken from Descriptors in Health Sciences (DeCS) at the review was conducted in: Google Scholar, PubMed Central, SciELO, and Infomed. Articles available in full text in Spanish and English were selected, with no restrictions as to the type of articles, from peer-reviewed journals and pages of recognized international organizations. The insulin resistance that accompanies obesity produces a chronic low-grade inflammatory state that leads to metabolic and hormonal disorders that increase the risk of severe disease by COVID-19, such as increased cellular entry of SARS-CoV-2 by increasing its cellular receptors, dysfunction of the immune response, altered hormone signaling, coagulopathy, and respiratory dysfunction.

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Author Biographies

Alexander Expósito Lara, Escuela Superior Politécnica de Chimborazo (ESPOCH). Riobamba. Chimborazo

Especialista en Medicina Crítica y Emergencias. Máster en Urgencias Médicas.

Gisela Eduarda Feria Díaz, Escuela Superior Politécnica de Chimborazo (ESPOCH). Riobamba. Chimborazo

Especialista en Medicina General Integral.

Pedro Enrique Miguel Soca, Universidad de Ciencias Médicas de Holguín. Holguín

Especialista de Segundo Grado en Bioquímica Clínica. Profesor Auxiliar. Investigador Auxiliar.

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Published

2022-05-01

How to Cite

Rodríguez Duque, R., Expósito Lara, A., Feria Díaz, G. E., & Miguel Soca, P. E. (2022). Obesity and COVID-19: a dangerous dyad. Anales De La Academia De Ciencias De Cuba, 12(2), e1180. Retrieved from https://revistaccuba.sld.cu/index.php/revacc/article/view/1180

Issue

Vol. 12 No. 2 (2022): mayo-agosto

Section

Biomedical sciences

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