Combined phacoemulsification whith modified gonio-assisted trabeculectomy in patient whit cataract and glaucoma
Keywords:
glaucoma, cataract, combined surgeryAbstract
Introduction: Cataract and glaucoma are the leading causes of blindness in Cuba and around the world. In this scenery many patients require combined surgery to treat both conditions and achieve visual recovery.
Objective: To determine the postoperative visual recovery, predictability, and refractive stability of phacoemulsification combined with modified gonioassisted trabeculectomy in the treatment of patients with cataract and primary open-angle glaucoma.
Methods: Experimental intervention study where 51 eyes were randomly operated with phacoemulsification combined with modified gonioassisted trabeculectomy and 52 eyes with phacoemulsification combined with trabeculectomy. They were studied from January 2017 to December 2019 at the Instituto Cubano de Oftalmología. The visual acuity and refractive status were evaluated in the preoperative period, at one month, three months and 24 months postoperatively.
Results: The proposed technique showed, one month after surgery, uncorrected visual acuity (0.8 ± 0.2), predictive error (0.17 ± 1.06 D) and induced astigmatism (0.70 ± 1.00 D), superior to phacoemulsification combined with trabeculectomy (p=0.001; p=0.004 and p=0.023).
Conclusions: The proposed surgical technique allows visual recovery with predictability and refractive stability from one month after surgery during the first 24 months postoperatively.
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References
1. Zhang JH, Ramke J, Lee CN, Gordon I, Safi S, Lingham G, et al. A Systematic Review of Clinical Practice Guidelines for Cataract: Evidence to Support the Development of the WHO Package of Eye Care Interventions. 2022. [citado 18 ene 2023];6(2):36. Disponible en: https://doi.org/10.3390/vision6020036
2. Tanna AP, Boland MV, Giaconi JA, Krishnan C, Lin SC, Medeiros FA. Basic and Clinical Science Course: Glaucoma. 2020-2021. San Francisco: American Academy of Ophthalmology; 2020.
3. Lorenzo RB, Rodríguez BNR, Torres MR, González CMP, Urbay JG, et al. Discapacidad visual y ceguera por catarata en Cuba en 2016. 2022 [citado 18 ene 2023];35(4). Disponible en: https://revoftalmologia.sld.cu/index.php/oftalmologia/article/view/1710
4. Wurster P, Harris A, Gonzalez AC, Adjei S, VerticchioVercellin A, Mathew S, et al. Risk factors for open-angle glaucoma in persons of Latin American descent. Journal of Glaucoma. 2020;29(3):217-25. Disponible en: https://doi.org/10.1097/IJG.0000000000001429
5. ONEI-CUBA. Anuario Estadístico de Cuba. 2023. Inst. Organización Nacional de Estadísticas e Información (ONEI). La Habana, Cuba; 2023. [citado 18 may 2025]. Disponible en: https://files.sld.cu/dne/files/2024/09/Anuario-Estad%3%astico-de-salud-2023-EDCION-2024.pdf
6. Albizu-Campos JC. Cuba: envejecimiento demográfico y desarrollo humano. Econ. y Desarrollo. 2020. [citado 18 ene 2023];164(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0252-5842020000200013
7. Gallego-Pinazo R, López E, Marín J. Resultados postquirúrgicos en la cirugía combinada de glaucoma: Comparación del implante express con la trabeculectomía estándar. Arch Soc Esp Oftalmol. 2009. [citado 18 ene 2023];84(6):293-7. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=626548
8. Francis B, Wang M, Lei H, Du L, Minckler D, Green R, et al. Changes in axial length following trabeculectomy and glaucoma drainage device surgery. British Journal of Ophthalmology. 2005;89(1):17-20. Disponible en: https://doi.org/10.1136/bjo.2004.043950
9. Husain R, Li W, Gazzard G, Foster PJ, Chew PT, Oen FT, et al. Longitudinal changes in anterior chamber depth and axial length in Asian subjects after trabeculectomy surgery. British Journal of Ophthalmology. 2013.;97(7):852-6. Disponible en: https://doi.org/10.1136/bjophthalmol-2012-302442
10. Lima FLd, Diniz-Filho A, Júnior E. Minimally Invasive Glaucoma Surgery (MIGS): an updated literature review. Revista Brasileira de Oftalmologia. 2022;81. Disponible en: https://doi.org/10.37039/1982.8551.20220105
11. Romero PR, Duch S, Moreno-Montañés J, Botella JB, Miró MB, Arenas J. Encuesta sobre las preferencias quirúrgicas entre los glaucomatólogos en España. Arch Soc Esp Oftalmol. 2022;97(6):310-6. Disponible en: https://doi.org/10.1016/j.oftal.2021.04.007
12. Tanito M. Microhook ab interno trabeculotomy, a novel minimally invasive glaucoma surgery. Clinical Ophthalmology. 2017:43-8. Disponible en: https://doi.org/10.2147/OPTH.S152406
13. Sato T, Hirata A, Mizoguchi T. Prospective, non-comparative, nonrandomized case study of short-term outcomes of 360 suture trabeculotomyabinterno in patients with open-angle glaucoma. ClinicalOphthalmology. 2015:63-8. Disponible en: https://doi.org/10.2147/OPTH.S75739
14. Fumero FY, Díaz IP, Baiocchi S, Hernández EA, Rangel YP. Implante Ex-PRESS mediante la técnica de Richard Hoffman. Rev. Cubana Oftalmol. 2020. [citado 18 ene 2023];33(4):1-12. Disponible en: https://www.medigraphic.com/pdfs/revcuboft/rco 2020/rco204l.pdf
15. Fumero FY, Piloto I, Fernández L, Domínguez M, Obret I, Chaviano G. Trabeculotomía gonioasistida modificada, una alternativa quirúrgica mínimamente invasiva para el glaucoma. Rev. Cubana de Oftalmol. 2018. [citado 18 ene 2023];31(3):1-9. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762018000300012
16. Fumero FY, Fernández L, Chaviano G, Pérez Y, Benavides AM. Resultados al año de la trabeculotomía gonioasistida modificada como alternativa mínimamente invasiva para el glaucoma. Rev. Cubana de Oftalmol. 2020. [citado 18 ene 2023];33(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762020000400002
17. Fumero González FY, Fernández L, Pérez Rangel Y, Herrera Padrón M. Complicaciones posoperatorias de la facoemulsificación asociada a trabeculectomía gonioasistida modificada con tijeras. Rev. Cubana de Oftalmol. 2023. [citado 18 ene 2023]; 36(1). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762023000100016
18. Lu Q, Wei L, He W, Zhang K, Wang J, Zhang Y, et al. Lens Opacities Classification System III–based artificial intelligence program for automatic cataract grading. Journal of Cataract & Refractive Surgery. 2022; 48(5):528-34. Disponible en: https://doi.org/10.1097/j.jcrs.0000000000000790
19. Brusini PJ. Global Glaucoma Staging System (GGSS): a new method to simultaneously assess the severity of both functional and structural damage in glaucoma. Journal of Clinical Medicine. 2021;10(19):4414. Disponible en: https://doi.org/10.3390/jcm10194414
20. Fumero-González FY. Glaucoma. Herramientas de diagnóstico y seguimiento. [Internet]. La Habana: Editorial Ciencias Médicas; 2022. Disponible en: http://www.bvs/sld.cu/libros/glaucoma_herramientas_diagnostico/índice/p.2022
21. Neeru G. Guías del Consejo Internacional de Oftalmología (ICO) para el Glaucoma. 2015. [citado 18 ene 2023];2-20. Disponible en: https://www.saludcastillayleon.es/guias-del-consejo-internacional-de oftalmologia-ico-para-el-glaucoma/
22. Rangaraj NR, Sathyan P. Interpretation of Octopus Visual Fields. En: Patyal S, Gandhi M. Resolving Dilemmas in Perimetry: Illustrated Manual of Visual Field Defects. Springer; 2021. p. 83-91. Disponible en: https://doi.org/10.1007/978-981-16-2601-2_
23. Mundial AM. Principios éticos para las investigaciones médicas en seres humanos. Declaración de Helsinki de la AMM; 2019. [citado 18 ene 2023]. Disponible en: http://www.wma.net/es/30publications/10policies/b3/
24. Jacobi PC, Dietlein TS, Krieglstein O. Comparative study of trabecular aspiration vs trabeculectomy in glaucoma triple procedure to treat pseudoexfoliation glaucoma. Archives of Ophthalmology. 1999;117(10):1311-8. Disponible en: https://doi.org/10.1001/archopht.117.10.1311
25. Ozturk E, Firat PG. Long-term effects of phacoemulsification surgery on intraocular pressure in patients with primary open-angle glaucoma and pseudoexfoliation glaucoma. Annals of Medical Research. 2020. [citado 27 may 2023];27(8),2112-7. Disponible en: https://annalsmedres.org/index.php/aomr/article/view/902
26. Iancu R, Corbu C. Intraocular pressure after phacoemulsification in patients with uncontrolled primary open angle glaucoma. Journal of Medicine and Life. 2014. [citado 18 ene 2023];7(1):11-6. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24653751/
27. Delavar A, Saseendrakumar BR, Weinreb RN, Baxter SL. Healthcare Access and Utilization Among Glaucoma Patients. Nationwide Cohort. Journal of Glaucoma. 2023;32(1):40-7. Disponible en: https://doi.org/10.1097/IJG.0000000000002123
28. Dorairaj SK, Kahook MY, Williamson BK, Seibold LK, ElMallah MK, Singh IP. A multicenter retrospective comparison of goniotomy versus trabecular bypass device implantation in glaucoma patients undergoing cataract extraction. Clinicalophthalmology (Auckland, NZ). 2018; 12:791-7. Disponible en: https://doi.org//10.2147/OPTH.S158403
29. Samuelson TW, Chang DF, Marqus R, Flowers B, Lim KS, Ahmed IIK, et al. A Schlemm Canal Microstent for Intraocular Pressure Reduction in Primary Open-Angle Glaucoma and Cataract: The HORIZON Study. Ophthalmology. 2019;126(1):29-37. Disponible en: https://doi.org//10.1016/j.ophtha.2018.05.012
30. Sarkisian SR, Jr., Radcliffe N, Harasymowycz P, Vold S, Patrianakos T, Zhang A, et al. Visual outcomes of combined cataract surgery and minimally invasive glaucoma surgery. Journal of cataract and refractive surgery. 2020;46(10):1422-32. Disponible en: https://doi.org//10.1097/j.jcrs.0000000000000317
31. ElMallah MK, Seibold LK, Kahook MY, Williamson BK, Singh IP, Dorairaj SK, et al. 12-month retrospective comparison of kahook dual blade excisional goniotomy with istent trabecular bypass device implantation in glaucomatous eyes at the time of cataract surgery. Advances in Therapy. 2019; 36:2515-27. Disponible en: https://doi.org/10.1007/s12325-019-010251
32. Sieck EG, Capitena Young CE, Epstein RS, SooHoo JR, Pantcheva MB, Patnaik JL, et al. Refractive outcomes among glaucoma patients undergoing phacoemulsification cataract extraction with and without Kahook Dual Blade goniotomy. Eye and Vis. 2019;6:1-6. Disponible en: https://doi.org/10.1186/s40662-019-0153-2
33. Scott RA, Ferguson TJ, Stephens JD, Berdahl JP. Refractive outcomes after trabecular microbypass stent with cataract extraction in open-angle glaucoma. Clinicalophthalmology (Auckland, NZ). 2019; 13:1331-40. Disponible en: https://doi.org/10.2147/OPTH.S206619
34. Chan HHL, Kong YXG. Glaucoma surgery and induced astigmatism: a systematic review. Eye and Vision. 2017. [citado 28 May 2023];4(1):27. Disponible en: https://eandv.biomedcentral.com/articles/10.1186/s40662-017-0090-x
35. Hernández I, Lu G, Cárdenas T. Comparación entre las fórmulas SRK/T, Hoffer Q, Barrett Universal y HRBF para el cálculo del lente intraocular. Rev. Cubana Oftalmol. 2021. [citado 18 ene 2023]; 34(4). Disponible en: https://revoftalmologia.sld.cu/index.php/oftalmologia/article/view/1737
36. Hernández López I, Cárdenas Díaz T. Impacto de la inteligencia artificial en la cirugía de catarata desde una perspectiva social. Rev. Cubana Oftalmol. 2021.[citado 22 Ene 2023];34(2). Disponible en: https://revoftalmologia.sld.cu/index.php/oftalmologia/article/view/1152
37. Lundström M, Dickman M, Henry Y, Manning S, Rosen P, Tassignon MJ, et al. Risk factors for refractive error after cataract surgery: Analysis of 282 811 cataract extractions reported to the European Registry of Quality Outcomes for cataract and refractive surgery. Journal of cataract and refractive surgery. 2018. [Citado 18 ene 2023];44(4):447-52. Disponible en: https://doi.org/10.1016/j.jcrs.2018.01.031
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