Past, present and future of classical Cuban veterinary vaccines: contribution to animal health
Keywords:
veterinary vaccines, platform technologies, vaccine manufacturingAbstract
Introduction. The gradual detection in Cuba of some infectious diseases such as avian smallpox, infectious bronchitis, infectious bursitis, avian pneumoencephalitis, blackleg, equine encephalomyelitis and bovine bacillary icterohemoglobinuria constituted a serious threat to the animal health system. To prevent the associated economic-productive effects, and avoid risking the national food security, it was established the use of nationally manufactured classic vaccines as a control strategy.
Objective: to demonstrate the health impact of the classic vaccines implemented in the period 1964-1993 and the relevance of continuing with the use of these technological platforms to manufacture them.
Methods: They were used estimates of prevalence and reemergence derived from the retrospective documentary review (2017-2022), as well as thematic searches in the Scopus database on veterinary vaccines and adjuvants (2008-2022).
Development: The classic vaccines progressively implemented in Cuba for 59 years, continue to generate favorable epidemiological behaviors in economic-productive species and, their production technology continues to be a relevant issue both for science and for the global veterinary biopharmaceutical sector.
Conclusions: The use of classic Cuban vaccines without interruptions or changes in the vaccination schedule favored the control of the seven diseases described with a favorable cost-benefit relation. The absence of change signs in the international scientific and commercial sector allowed us to infer that, in short term, there will be no changes that affect the hegemony of the classic vaccines adjuvanted with aluminum hydroxide, despite the advances in genetic engineering and biotechnology.Downloads
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