New statistical analysis methodology in health problems research
Keywords:
methodology, statistics, implicative statistical analysis, medical research, causality, interpretation of resultsAbstract
Introduction: Traditional statistical techniques used to study causality are based on the assumption of linearity, even though the complexity of health-disease processes is known.
Objective: To describe the foundations, design and validation of a methodology for the application of implicative statistical analysis in medical causality research and to evaluate its effectiveness in solving a specific health problem.
Methods: The design of the proposed methodology was based on the articulation of procedures developed from previously identified limitations. Validation was carried out through 3 studies. The first one for criterion corroboration through comparison with binary logistic regression. The second one for content validation allowed verifying the correspondence of the rules obtained with what was proposed in the literature. In addition, most of these rules were classified, according to the experts criteria, as correct, and a favorable opinion was issued on the methodology by its potential users. The third study was a meta-analysis that summarized the indicators obtained in the studies that applied the methodology, which also corroborated its good performance.
Results: By evaluating the effectiveness of the methodology, it was possible to identify the prognostic factors of mortality due to breast cancer in the province of Santiago de Cuba.
Conclusions: The methodology constitutes a new perspective of data analysis and interpretation of results, which contributes to improving causality research in medicine, therefore, its use in these studies is recommended.
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