Anatomic and functional evaluation of sensory systems in mesial temporal lobe epileptic patients after surgical treatment

Authors

Keywords:

auditory pathway, magnetic resonance, perimetry, temporal lobe epilepsy, visual pathway

Abstract

Introduction: The present investigation studies, for the first time in our country, the consequences on the sensory auditory and visual systems after surgery for drug resistant temporal lobe epileptic patients. Objectives: The aim of the study was to evaluate the anatomic and functional changes after electrocorticography-guided anterior-temporal
lobectomy.
Methods: A sample of 28 patients that underwent surgery for drug resistant temporal lobe epilepsy was studied. The surgery was performed at the International Center for Neurological Restoration (CIREN) between years 2002-2012.
Results: Functional alterations in the visual and auditory systems were detected even before surgery. After surgery further auditory alterations were detected by auditory evoked potentials, likely as an indirect, long-term consequence of the resection of specific structures like the amygdala and the medial temporal pole. On the visual system, the resection of the epileptogenic zone provoked visual deficits, evidenced by visual perimetry combined with quadrant-restricted visual evoked potentials. The visual defects are in good correspondence with the amount of resected tissue. Lesions within the visual pathway were confirmed by optic radiation tractography and connectivity studies. Conclusions: indirect and long term functional changes of the auditory pathway were described, while direct lesions of the visual pathway were confirmed with objective methods of exploration, according to the surgical resection magnitude.

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Author Biography

Margarita Minou Baez-Martin, Centro Internacional de Restauración Neurológica

Departamento Neurofisiología Clínica J´Laboratorio Potenciales Evocados

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Published

2021-04-27

How to Cite

Baez-Martin, M. M., Morales Chacón, L., García Maeso, I., Lorigados Pedre, L., Estupiñán Díaz, B., García Navarro, M. E., … Galvizu Sánchez, R. (2021). Anatomic and functional evaluation of sensory systems in mesial temporal lobe epileptic patients after surgical treatment. Anales De La Academia De Ciencias De Cuba, 11(2), e841. Retrieved from https://revistaccuba.sld.cu/index.php/revacc/article/view/841

Issue

Vol. 11 No. 2 (2021): mayo-agosto

Section

Biomedical sciences

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