SARS-CoV-2 infection: from neuroinvasive mechanisms to neurological manifestations

Authors

  • Juan Enrique Bender del Busto Centro Internacional de Restauración Neurológica
  • Roberto León Castellón
  • Marcel D. Mendieta Pedroso Hospital Leopoldito Martínez; San José de las Lajas,
  • Roberto Rodríguez Labrada Centro de Neurociencias de Cuba
  • Luis C. Velázquez Pérez Presidente de la Academia de Ciencias de Cuba

Keywords:

coronavirus, neurotropism, neurological manifestations, COVID-19

Abstract

In December 2019, cases related to a new coronavirus were detected; causing an acute respiratory syndrome, later named SARS-CoV-2 and, after the consequent disease, coronavirus disease 2019 (COVID-19). This virus spread rapidly throughout Europe and America, causing great morbidity and mortality, in turn, declaring a pandemic by the World Health Organization on March 11, 2020. Taking into account the virus's neurotropism, are reported by various authors, the various neurological manifestations that have occurred, both in the central and peripheral nervous systems, during COVID-19, including in the early stages, which could worsen the prognosis. An analytical summary of the scientific evidence available regarding the involvement of the nervous system by the coronavirus 2019 is performed. The manifestations of the nervous system due to SARS-CoV-2 infection are highlighted and the importance of taking into account chronic neurological pathologies that may have an implication in the unfavorable evolution of the disease is highlighted. Clinical evaluation and the performance of other examinations in affected patients are necessary to monitor them during and after illness.

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Published

2020-05-15

How to Cite

Bender del Busto, J. E., León Castellón, R., Mendieta Pedroso, M. D., Rodríguez Labrada, R., & Velázquez Pérez, L. C. (2020). SARS-CoV-2 infection: from neuroinvasive mechanisms to neurological manifestations. Anales De La Academia De Ciencias De Cuba, 10(2), e855. Retrieved from https://revistaccuba.sld.cu/index.php/revacc/article/view/855

Issue

Vol. 10 No. 2 (2020): mayo-agosto (especial COVID-19)

Section

Biomedical sciences

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